Zipline Application Paths
All applications submitted in Zipline follow one of three review paths. Selecting the correct path before starting your application helps avoid delays and rework.
If you are unsure which path applies to your study, consult HSD by emailing hsdrely@uw.edu before starting.
Option 1: 91±¬ÁÏ Reviewing for 91±¬ÁÏ Only
Choose this option if:
- The research may be exempt (HSD must make this determination), and/or
- The research involves only the 91±¬ÁÏ, or
- Other institutions are involved, but 91±¬ÁÏ will not review on their behalf (for example, the 91±¬ÁÏ IRB generally does not review for the VA).
Key points:
Next step:
Option 2: 91±¬ÁÏ Reviewing for Other Institutions
Choose this option if:
Key points:
- HSD must agree in advance to review for other institutions and establish reliance agreements
- Approval under this path does not approve all sites at once
- Each relying institution goes through a separate site review and receives a separate site approval
Common examples:
- 91±¬ÁÏ is the primary recipient of a federal award for a multi site NIH grant
- Collaborations with local partners (e.g., Seattle Children’s or Fred Hutch) where 91±¬ÁÏ is the primary awardee
- International studies where 91±¬ÁÏ is the primary recipient of a federal award
Next steps:
Option 3: Non-91±¬ÁÏ IRB Reviewing
Choose this option if:
- The research requires IRB review and
- 91±¬ÁÏ should not serve as the reviewing IRB.
Key points:
- HSD must agree in advance to cede IRB review and establish reliance agreements
Common examples:
- An external IRB is designated by the sponsor
- The study is industry sponsored
- 91±¬ÁÏ is participating as a relying site in a multi site study
Next steps: