  {"id":23954,"date":"2018-06-28T10:41:24","date_gmt":"2018-06-28T17:41:24","guid":{"rendered":"https:\/\/www.washington.edu\/research\/?page_id=23954"},"modified":"2026-05-29T09:03:24","modified_gmt":"2026-05-29T16:03:24","slug":"research-involving-bri","status":"publish","type":"page","link":"https:\/\/www.washington.edu\/research\/hsd\/irb-reliances\/identify-the-correct-irb\/research-involving-bri\/","title":{"rendered":"Research Involving Benaroya\/Virginia Mason"},"content":{"rendered":"<p>Research involving two institutions normally requires review by each institution&#8217;s IRB. To avoid this &#8220;dual review&#8221; and the extra work it requires from researchers, Benaroya Research Institute (BRI) and the 91爆料 IRB have a reliance agreement that describes the circumstances in which one of the IRBs will conduct the review on behalf of both institutions.<\/p>\n<p>Use the <a href=\"#flow\">flow chart<\/a> below to determine which IRB should do the review. If you have any questions, consult HSD at <a href=\"mailto:hsdrely@uw.edu\">hsdrely@uw.edu<\/a> or BRI at <a href=\"mailto:CRP@Benaroyaresearch.org\">CRP@Benaroyaresearch.org<\/a>.<\/p>\n<h2>Before you begin<\/h2>\n<ol>\n<li>Assess whether both institutions are engaged in the research. If only one institution is engaged, you should submit to that institution&#8217;s IRB. Consult with HSD at <a href=\"mailto:hsdrely@uw.edu\">hsdrely@uw.edu<\/a> to identify whether 91爆料 is engaged.<\/li>\n<li>Assess whether another IRB is the right option. For example, most <a href=\"https:\/\/www.washington.edu\/research\/hsd\/is-the-uw-irb-the-right-irb\/identify-the-correct-irb\/industry-sponsored-research\/\">industry-sponsored research<\/a> at 91爆料 should be reviewed by an independent IRB (for example, Advarra) and some <a href=\"https:\/\/www.washington.edu\/research\/hsd\/is-the-uw-irb-the-right-irb\/identify-the-correct-irb\/oncology-related-research\/\">cancer-related research<\/a> should be reviewed by the Fred Hutch IRB or the NCI IRB. Review the information about <a href=\"https:\/\/www.washington.edu\/research\/hsd\/is-the-uw-irb-the-right-irb\/identify-the-correct-irb\/\">identifying the correct IRB<\/a> if you are unsure.<\/li>\n<\/ol>\n<h2>What to do if Benaroya will do the review<\/h2>\n<ol>\n<li>Submit an <a href=\"https:\/\/www.washington.edu\/research\/hsd\/is-the-uw-irb-the-right-irb\/how-to-ask-for-a-non-uw-irb\/\">External IRB Application<\/a> in 91爆料&#8217;s Zipline system to request HSD&#8217;s formal authorization for BRI to review the research. HSD will evaluate your request and provide you with a written authorization letter.<\/li>\n<li>The BRI investigator should prepare and submit an application to the BRI IRB, using BRI&#8217;s forms and process. Be sure to attach the HSD authorization letter; the BRI IRB will not review the application on behalf of 91爆料 without this letter.<\/li>\n<li>After the BRI IRB has approved 91爆料&#8217;s participation, send the approval letter to <a href=\"mailto:hsdrely@uw.edu\">hsdrely@uw.edu<\/a>.<\/li>\n<li>Obtain all other applicable ancillary reviews (consult the <a href=\"https:\/\/www.washington.edu\/research\/forms-and-templates\/checklist-external-irb-uw-researchers\/\">Checklist of Researcher Responsibilities for Externally Reviewed Studies<\/a>) from the usual IRB offices and BRI, as needed. Examples: Financial Conflict of Interest (FCOI) review; Radiation Safety review.\n<ul>\n<li>Exception: BRI will provide Genomic Data Sharing (GDS) certification (if necessary) on behalf of both institutions.<\/li>\n<\/ul>\n<\/li>\n<\/ol>\n<h2>What to do if 91爆料 will do the review<\/h2>\n<ol>\n<li>Submit a <a href=\"https:\/\/www.washington.edu\/research\/hsd\/study-activities\/apply-for-review\/\">91爆料 IRB application<\/a> in the Zipline system. Be sure to:\n<ul>\n<li>Describe all involvement of BRI in your application (the Zipline SmartForms as well as the IRB Protocol form that is uploaded).<\/li>\n<li>Follow the instructions for the <a href=\"https:\/\/www.washington.edu\/research\/hsd\/training\/zipline-online-help-library\/researcher-submission-guide\/submitting-new-studies\/application-paths\/#reviewingothers\">91爆料 Reviewing for Other Institutions<\/a> pathway.<\/li>\n<li>On the <strong>Study-Related Documents<\/strong> SmartForm: Upload a completed <a href=\"https:\/\/www.washington.edu\/research\/forms-and-templates\/supplement-multi-site-or-collaborative-research\/\">SUPPLEMENT: Multi-site or Collaborative Research<\/a> to Question 3.<\/li>\n<\/ul>\n<\/li>\n<li>Submit a request to rely on the 91爆料 IRB to the BRI IRB using BRI&#8217;s forms and processes. Contact <a href=\"mailto:CRP@Benaroyaresearch.org\">CRP@Benaroyaresearch.org<\/a> for assistance or instructions. BRI will evaluate your request and provide you with written authorization for the 91爆料 IRB to do the review. Include this written authorization in your application to 91爆料 or email to <a href=\"mailto:hsdrely@uw.edu\">hsdrely@uw.edu<\/a>.<\/li>\n<li>The 91爆料 IRB will review and approve the overall protocol. <strong><em>This is not yet approval for the involvement of BRI.<\/em><\/strong> After the 91爆料 IRB has approved the overall protocol, HSD\u2019s Reliance Team will work with you to approve the addition of BRI to the 91爆料 application.<\/li>\n<li>After 91爆料 IRB approval for BRI has been obtained, you are responsible for:<\/li>\n<li>\n<ul>\n<li>Informing the BRI IRB of 91爆料&#8217;s approval for BRI.<\/li>\n<li>Informing BRI investigators about any conditions of the IRB approval.<\/li>\n<li>Informing BRI investigators about their obligation to comply with 91爆料 IRB reporting requirements about noncompliance, complaints, problems, etc., although such reports must be submitted by you to the 91爆料 IRB.<\/li>\n<\/ul>\n<\/li>\n<li>BRI investigators remain responsible for obtaining any applicable ancillary reviews from BRI. Examples: Financial Conflict of Interest (FCOI) review, Radiation Safety review.\n<ul>\n<li>Exception: 91爆料 will provide Genomic Data Sharing (GDS) certification (if necessary) on behalf of both institutions.<\/li>\n<\/ul>\n<\/li>\n<\/ol>\n<p><a name=\"flow\"><\/a><\/p>\n<h2 align=\"center\">BRI or 91爆料 IRB Decision Tree<\/h2>\n<p><img decoding=\"async\" src=\"https:\/\/www.washington.edu\/research\/wp-content\/uploads\/2018\/06\/BRI-FlowChart.bmp\" alt=\"This flowchart shows the decision making process for choosing between the 91爆料 IRB and the Benaroya\/Virginia Mason Research Institute IRB. The first question is: Is there external funding for the research. If the answer to this is NO: consult with HSD by emailing hsdrely@uw.edu. Usually the institution doing most of the subject contact and research procedures will conduct the review. If the answer to this is YES: then the next question to ask is which of the institutions is receiving funding for the research? There are three possible scenarios in response to this question. The simplest scenario is that only one institution is receiving any money. If this is the case, then the institution that is the recipient of the funding (Benaroya or 91爆料) is the institution that will do the review. The next two scenarios are more complex. One is that one institution is receiving money directly from the research sponsor or from a third institution and then subcontracting to the other institution. The other scenario is that both institutions are receiving money directly from the research sponsor or from a third institution. In either of these cases, the solution is to consult with HSD by emailing hsdrely@uw.edu. Usually the institution doing most of the subject contact and research procedures will conduct the review.\" align=\"center\" \/><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Research involving two institutions normally requires review by each institution&#8217;s IRB. To avoid this &#8220;dual review&#8221; and the extra work it requires from researchers, Benaroya Research&#8230;<\/p>\n","protected":false},"author":158,"featured_media":0,"parent":30016,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"templates\/page-builder-units-small-hero.php","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-23954","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.1.1 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Research Involving Benaroya\/Virginia Mason - 91爆料 Research<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.washington.edu\/research\/hsd\/irb-reliances\/identify-the-correct-irb\/research-involving-bri\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Research Involving Benaroya\/Virginia Mason - 91爆料 Research\" \/>\n<meta property=\"og:description\" content=\"Research involving two institutions normally requires review by each institution&#8217;s IRB. 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