Why is it important to study mosquitoes?听

Willem Laursen: Mosquitoes have been an enduring scourge of humanity for millennia. Their bites are a nuisance to humans and animals alike, and ancient texts describe illnesses consistent with mosquito-borne diseases, such as malaria, long before the source of transmission was understood.

Globalization and climate change are expanding the geographic range of many mosquito species, and their increasing resistance to insecticides threatens the long-term effectiveness of current control strategies. As a result, we urgently need new approaches for controlling mosquito-borne disease.

If we can better understand the genetic and sensory basis of mosquito behavior, we might be able to find new opportunities to disrupt disease transmission. Critical behaviors such as host seeking and blood feeding are highly specialized and difficult to model in other organisms, making it essential to study these mechanisms directly in mosquitoes themselves.

Andrea Durant: These mosquito-related problems are not just for humans. Warmer winters and early-season snowmelt have led to massive swarms of mosquitoes coinciding with wildlife migration, which changes foraging patterns in the Arctic tundra and forces animals like caribou to use precious energy reserves on evading these mosquito-blackened skies. Mosquito swarms are also a big problem for agriculture, particularly cattle herds.

What do you study?

AD: My lab studies how mosquitoes maintain a stable internal environment when faced with changing external conditions. Mosquitoes start their life as an egg that is deposited in or near water, and the larval, or juvenile, stages are aquatic. Unlike the terrestrial flying adult mosquito that has agency in its choice of residence, a mosquito larva is tied to wherever it hatches 鈥� it must survive and develop there, or die.

Sometimes the aquatic reservoirs where an adult female has selected to lay her eggs can be quite extreme, such as very polluted freshwater and seawater. We study specialized adaptations that allow these larvae to survive 鈥� most mosquito species require clean freshwater for larval development. Our goal is to reveal how mosquitoes have been able to successfully expand their habitats to places like urban sewage systems and salty coastal habitats.

WL: In my lab, our research focuses on understanding how mosquitoes sense things at the cellular level. We are trying to determine what proteins mosquitoes use to detect human-associated cues, such as heat and humidity. By identifying the cellular and molecular machinery mosquitoes use to find hosts, food sources, mates and egg-laying sites, we hope to better understand how specialized behaviors, such as blood feeding, evolve, and to uncover new targets for controlling the transmission of mosquito-borne diseases.

Jeffrey Riffell: My lab studies the 鈥渉ow鈥� of mosquito biting behavior. We also study how they visit flowers and plants 鈥� yes, they can pollinate certain plants! 鈥� to understand their natural behaviors. By learning more about mosquito physiology and behavior, we would like to develop new tools for traps and ways to control mosquitoes around people’s homes.

Tell us what it’s like to be someone who studies mosquitoes.

JR: Mosquitoes, all day and all the time. Although we try to minimize the potential for mosquito biting in the lab and in our field sites, you have to grin and bear it when dealing with these little vampires.听

WL: Being around large swarms of mosquitoes all day does desensitize me a bit. Sometimes I will be out hiking or camping with family members and I won’t be paying much attention until I start hearing complaints about the mosquitoes. Working with mosquitoes also leads me to do funny things, such as collecting sweat or wearing a nylon stocking for days to collect human odors for behavioral assays.

Rearing transgenic mosquitoes in the lab is a bit like ranching: We have to keep track of large herds of animals. Because the life stages live in different environments, we have to constantly shuttle them around between water-filled trays, for the larvae/pupae, and cages, for the terrestrial adults. We also have to move the adults around on a specific schedule to make sure they have access to our artificial blood feeders. Some lab members jokingly put a sign on the door that says “Welcome to The Ranch.”

AD: Willem is to a rancher as I am to a protagonist in “Swamp People.” We often venture outside of the lab to hunt mosquitoes in their natural habitat in urban and peri-urban areas. Sometimes we find ourselves in picturesque places like the beautiful pillow basalt coastlines of the San Juan Islands. Most often, I can be found headfirst in a nutrient-rich septic system in someone’s backyard filled with mosquito larvae or marching into the fray of massive swarms of saline-tolerant mosquitoes that await in tidal marshlands and mangrove forests.

What is the coolest mosquito fact you know?

WL: There are over 3,500 species of mosquitoes, with vastly different appearances, life histories and host preferences. Many are generalists. A few strongly prefer humans and some feed from cold-blooded animals like frogs or earthworms. The large amber-encased Toxorhynchites elephant mosquito shown in the movie “Jurassic Park” feeds on other mosquito larvae and doesn鈥檛 actually drink blood at all.

JR: I like These mosquitoes are very pretty, and they shoot their eggs into tree holes.

What鈥檚 one thing you wish people understood about mosquitoes?

AD: The incalculable misery that mosquitoes exert on humans and other animals certainly overshadows any appreciation for the importance of mosquitoes in nature. Many species of mosquitoes are critical to biodiversity and are actually fundamental to the food chain. There are numerous examples of areas with reduced breeding success and animal survival because there have been effective vector control programs and non-targeted mosquito eradication efforts.

For more information, contact Laursen at wlaursen@uw.edu, Durant at durantan@uw.edu and Riffell at jriffell@uw.edu.

Five 91爆料 faculty members have been awarded early-career fellowships from the Alfred P. Sloan Foundation. The new Sloan Fellows, announced Feb. 17, are , an assistant professor of physics, , an assistant professor of chemistry, and , an assistant professor of biology, all in the College of Arts & Sciences; , an assistant professor of computer science in the College of Engineering; and , an assistant professor of oceanography in the College of the Environment.听

Since the first Sloan Research Fellowships were awarded in 1955, and including this year鈥檚 fellows, 136 faculty from 91爆料 have received a Sloan Research Fellowship, according to the Sloan Foundation.听

Sloan Fellowships are open to scholars in seven scientific and technical fields 鈥� chemistry, computer science, Earth system science, economics, mathematics, neuroscience and physics 鈥� and honor early-career researchers whose achievements mark them among the next generation of scientific leaders.听

The 126鈥疭loan Fellows for 2026鈥痺ere selected by researchers and faculty in the scientific community. Candidates are nominated by their peers, and fellows are selected by independent panels of senior scholars based on each candidate鈥檚 research accomplishments, creativity and potential to become a leader in their field. Each fellow will receive $75,000 to apply toward research endeavors.听

This year鈥檚 fellows come from 44 institutions across the United States and Canada.听

Maria 鈥淢asha鈥� Baryakhtar

叠补谤测补办丑迟补谤鈥檚 research in the Department of Physics focuses on theories beyond the established Standard Model of particle physics and on creating new ideas and directions for testing these theories. Such theories address outstanding puzzles in our existing understanding and often predict new, ultralight, feebly interacting particles beyond those we have discovered so far. The existence of these particles can be tested through exquisitely precise experiments in the lab or by observing extreme objects in the sky like black holes and neutron stars.

鈥淢y research program aims to search high and low for new, as yet hidden particles and forces. Because of their nature, these particles require a range of creative search strategies. The directions I am establishing use new technologies and data from the sky to the lab and may be the only way to shed light on the truly dark elements of our universe.鈥�

Matthew R. Golder

骋辞濒诲别谤鈥檚 research in the Department of Chemistry addresses the omnipresent “plastics problems” from two different vantage points. First, the team thinks about new ways to prolong the useful lifetime of commodity materials. The researchers use molecular engineering to keep plastics in use longer before discarding. The Golder Research Group also develops new methods to make and repurpose plastics, with an emphasis on green chemistry and making plastics more recyclable.

“Plastics are paramount to daily life, so there are numerous opportunities to improve performance and mitigate waste. We operate at the interface of fundamental organic chemistry and applied materials science to enhance plastic integrity and sustainability. By doing so, my students really take this mission to heart and constantly dream up new ways to creatively (re)design commodity plastic materials.”听

Vikram Iyer

滨测别谤鈥檚 research in the Paul G. Allen School of Computer Science & Engineering seeks to address sustainability challenges across the full computing stack from creating recyclable polymers to reimagining the way we build computing hardware by designing AI systems to and . In particular, the group鈥檚 work goes beyond simply reducing energy consumption to quantify and tackle the environmental impacts of materials and manufacturing.听

鈥�My group both leverages innovations from outside of computing like chemistry and material science to drive sustainability and applies computing techniques from AI to programming languages to fundamentally advance environmental sciences. This work is highly interdisciplinary and takes some extra effort at the beginning for each of us to understand the technologies and methods developed by our collaborators. By doing this, we can come up with completely new ideas that have real world impact like enabling carbon reduction at major companies like Amazon, and creating systems like battery-free robots that push the boundaries of technology.鈥�

Willem Laursen

尝补耻谤蝉别苍鈥檚 research in the Department of Biology is focused on understanding how animals detect and respond to sensory cues in their environment. Using genetic manipulation, neurophysiology and behavioral analyses, the lab’s current focus is to understand how disease vector mosquitoes use sensory cues to locate hosts, mates and egg-laying sites.

“It is an honor to be selected as a Sloan Fellow. This award will support our lab鈥檚 research on the role of the mosquito gustatory, or taste, system in critical behaviors, such as blood feeding. While mosquitoes use all of their senses to efficiently locate hosts, their taste system is surprisingly understudied. By examining the gustatory systems of blood-feeding insects, we hope to better understand how taste cues on the skin and in the blood are detected and used to guide their specialized behaviors, lines of inquiry that could ultimately identify new targets for controlling the spread of disease.”

Frankie Pavia

笔补惫颈补鈥檚 research in the School of Oceanography develops and applies new isotopic techniques to study feedbacks in the Earth system. His work spans the oceanic, atmospheric, lithospheric, and human domains, on timescales ranging from minutes to millennia.

鈥淭he oceans are a repository and reactor for materials originating on land, in the atmosphere, in Earth鈥檚 interior and from outer space. Chemical fingerprints of oceanic interactions with these reservoirs can be unlocked using unique analytical chemistry techniques, especially those involving the precise measurement of isotope ratios. My current research aims to discover new interactions between the oceans and the Earth system in the past, present and future, by pioneering interdisciplinary studies that use measurements of stable and radioactive isotopes to determine how much and how fast the Earth system changes. Current projects involve using cosmic dust to reconstruct sea-ice coverage, sensitively detecting human-derived carbon in the oceans, and understanding the past and future impacts of oceanic calcium carbonate dissolution on storage of atmospheric carbon dioxide.鈥澨�

Contact Baryakhtar at mbaryakh@uw.edu, Golder at goldermr@uw.edu, Iyer at vsiyer@cs.washington.edu, Laursen at wlaursen@uw.edu, and Pavia at fjpavia@uw.edu.