Fred Hutchinson Cancer Center – 91爆料 News /news Tue, 25 Nov 2025 18:05:25 +0000 en-US hourly 1 https://wordpress.org/?v=6.9.4 Clarivate Highly Cited Researchers 2025 list includes 56 91爆料 faculty and researchers /news/2025/11/25/clarivate-highly-cited-researchers-2025-list-includes-56-uw-faculty-and-researchers/ Tue, 25 Nov 2025 18:05:25 +0000 /news/?p=89946 aerial view of a college campus in autumn
The91爆料 has 56 faculty and researchers named on the Highly Cited Researchers 2025 list from Clarivate. Photo: Mark Stone/91爆料

The 91爆料 is proud to announce that 56 faculty and researchers who completed their work while at 91爆料 have been named on the list from Clarivate.

The annual list identifies researchers who demonstrated significant influence in their chosen field or fields through the publication of multiple highly cited papers during the last decade. Their names are drawn from the publications that rank in the top 1% by citations for field and publication year in the .

Highly Cited Researchers demonstrate significant and broad influence in their fields of research. The total list includes 7,131 awards from more than 1,300 institutions in 60 countries and regions. This small fraction of the global researcher population contributes disproportionately to extending the frontiers of knowledge and contributing to innovations that make the world healthier, more sustainable and which drive societal impact, according to Clarivate.

The that determines the 鈥渨ho鈥檚 who鈥 of influential researchers is drawn from data and analysis performed by bibliometric experts and data scientists at the Institute for Scientific Information at Clarivate.

The list below includes faculty and researchers whose primary affiliation is with the 91爆料, Fred Hutch Cancer Center, and the Institute for Health Metrics and Evaluation.

Please note: Some of the people on the list are no longer with the 91爆料 and their current affiliation is noted. This list reflects initial data from Clarivate and may be updated.

Ivan Anishchenko (Vilya)

David Baker

William A. Banks

Gregory N. Bratman

Steven L. Brunton

Guozhong Cao

Ting Cao

Lauren Carter (Gates Medical Research Institute)

Helen Chu

David H. Cobden

Katharine H. D. Crawford

Riza M. Daza

Frank DiMaio

Kristie L. Ebi

Evan E. Eichler

Emmanuela Gakidou

David Ginger

Raphael Gottardo (CHUV)

Alexander L. Greninger

Simon I. Hay

Andrew Hill (Infinimmune)

Eric Huang

Michael C. Jensen (BrainChild)

Neil P.聽 King

C. Dirk Keene

J. Nathan Kutz

Eric H. Larson

Aaron Lyon

Michael J. MacCoss

Brendan MacLean

C. M. Marcus

Julian D. Marshall

Ali Mokdad

Thomas J. Montine (Stanford)

Mohsen Naghavi

Marian L. Neuhouser

Julian D. Olden

Robert W. Palmatier

David Pigott

Hannah A. Pliner (Bristol Myers Squibb)

Ganesh Raghu

Stanley Riddell

Andrea Schietinger (Memorial Sloan Kettering Cancer Center)

Jay Shendure

M. Alejandra Tortorici

Troy R. Torgerson (Allen Institute)

Cole Trapnell

Katherine R. Tuttle

David Veesler

Theo Vos

Alexandra C. Walls (BioNTech SE)

Bryan J. Weiner

Di Xiao

Jie Xiao

Xiaodong Xu

Jihui Yang

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15 91爆料 professors among new class of members to the Washington State Academy of Sciences /news/2024/08/01/wsas-2024/ Thu, 01 Aug 2024 18:46:33 +0000 /news/?p=85954

UPDATE (Aug. 2, 2024): A previous version of this story misstated Paul Kinahan’s name.

Fifteen faculty members at the 91爆料 have been elected to the Washington State Academy of Sciences. They are among 36 scientists and educators from across the state . Selection recognizes the new members鈥 鈥渙utstanding record of scientific and technical achievement, and their willingness to work on behalf of the academy to bring the best available science to bear on issues within the state of Washington.鈥

Twelve 91爆料 faculty members were selected by current WSAS members. They are:

  • , associate professor of epidemiology, of health systems and population health, and of child, family and population health nursing, who 鈥減ossesses the rare combination of scientific rigor and courageous commitment to local community health. Identifying original ways to examine questions, and seeking out appropriate scientific methods to study those questions, allow her to translate research to collaborative community interventions with a direct impact on the health of communities.鈥
  • , the Shauna C. Larson endowed chair in learning sciences, for 鈥渉is work in the cultural basis of scientific research and learning, bringing rigor and light to multiculturalism in science and STEM education through STEM Teaching Tools and other programs.鈥
  • , professor of psychiatry and behavioral sciences, 鈥渇or her sustained commitment to community-engaged, science-driven practice and policy change related to the prevention of suicide and the promotion of mental health, with a focus on providing effective, sustainable and culturally appropriate care to people with serious mental illness.鈥
  • , the David and Nancy Auth endowed professor in bioengineering, who has 鈥渃harted new paths for 30-plus years. Her quest to deeply understand protein folding/unfolding and the link to amyloid diseases has propelled her to pioneer unique computational and experimental methods leading to the discovery and characterization of a new protein structure linked to toxicity early in amyloidogenesis.鈥
  • , professor of environmental and occupational health sciences, of global health, and of emergency medicine, who is 鈥渁 global and national leader at the intersection of climate change and health whose work has advanced our understanding of climate change health effects and has informed the design of preparedness and disaster response planning in Washington state, nationally and globally.鈥
  • , professor of bioengineering and of radiology, who is 鈥渞ecognized for his contributions to the science and engineering of medical imaging systems and for leadership in national programs and professional and scientific societies advancing the capabilities of medical imaging.鈥
  • , the Donald W. and Ruth Mary Close professor of electrical and computer engineering and faculty member in the 91爆料 Clean Energy Institute, who is 鈥渞ecognized for his distinguished research contributions to the design and operation of economical, reliable and environmentally sustainable power systems, and the development of influential educational materials used to train the next generation of power engineers.鈥
  • , senior vice president and director of the Vaccine and Infectious Disease Division at the Fred Hutchinson Cancer Center, the Joel D. Meyers endowed chair of clinical research and of vaccine and infectious disease at Fred Hutch, and 91爆料 professor of medicine, who is 鈥渋s recognized for her seminal contributions to developing validated laboratory methods for interrogating cellular and humoral immune responses to HIV, TB and COVID-19 vaccines, which has led to the analysis of more than 100 vaccine and monoclonal antibody trials for nearly three decades, including evidence of T-cell immune responses as a correlate of vaccine protection.鈥
  • , professor of political science and the Walker family professor for the arts and sciences, who is a specialist 鈥渋n environmental politics, international political economy, and the politics of nonprofit organizations. He is widely recognized as a leader in the field of environmental politics, best known for his path-breaking research on the role firms and nongovernmental organizations can play in promoting more stringent regulatory standards.鈥
  • , the Ballmer endowed dean of social work, for investigations of 鈥渉ow inequality, in its many forms, affects health, illness and quality of life. He has developed unique conceptual frameworks to investigate how race, ethnicity and immigration are associated with health and social outcomes.鈥
  • , professor of chemistry, who is elected 鈥渇or distinguished scientific and community contributions to advancing the field of electron paramagnetic resonance spectroscopy, which have transformed how researchers worldwide analyze data.鈥
  • , professor of bioengineering and of ophthalmology, whose 鈥減ioneering work in biomedical optics, including the invention of optical microangiography and development of novel imaging technologies, has transformed clinical practice, significantly improving patient outcomes. Through his numerous publications, patents and clinical translations, his research has helped shape the field of biomedical optics.鈥

Three new 91爆料 members of the academy were selected by virtue of their previous election to one of the National Academies. They are:

  • , professor of atmospheric and climate science, who had been elected to the National Academy of Sciences 鈥渇or contributions to research and expertise in atmospheric radiation and cloud processes, remote sensing, cloud/aerosol/radiation/climate interactions, stratospheric circulation and stratosphere-troposphere exchanges and coupling, and climate change.鈥
  • , the Bartley Dobb professor for the study and prevention of violence in the Department of Epidemiology and a 91爆料 professor of pediatrics, who had been elected to the National Academy of Medicine 鈥渇or being a national public health leader whose innovative and multidisciplinary research to integrate data across the health care system and criminal legal system has deepened our understanding of the risk and consequences of firearm-related harm and informed policies and programs to reduce its burden, especially among underserved communities and populations.鈥
  • , division chief of general pediatrics at Seattle Children鈥檚 Hospital and a 91爆料 professor of pediatrics, who had been elected to the National Academy of Medicine 鈥渇or her leadership in advancing child health equity through scholarship in community-partnered design of innovative care models in pediatric primary care. Her work has transformed our understanding of how to deliver child preventive health care during the critical early childhood period to achieve equitable health outcomes and reduce disparities.鈥

In addition, Dr. , president and director of the Fred Hutchinson Cancer Center and of the Cancer Consortium 鈥 a partnership between the 91爆料, Seattle Children鈥檚 Hospital and Fred Hutch 鈥 was elected to the academy for being 鈥減art of a research effort that found mutations in the cell-surface protein epidermal growth factor receptor (EGFR), which plays an important role in helping lung cancer cells survive. Today, drugs that target EGFR can dramatically change outcomes for lung cancer patients by slowing the progression of the cancer.鈥

the Boeing-Egtvedt endowed professor and chair in aeronautics and astronautics, will join the board effective Sept. 30. Morgansen was elected to WSAS in 2021 鈥渇or significant advances in nonlinear methods for integrated sensing and control in engineered, bioinspired and biological flight systems,鈥 and 鈥渇or leadership in cross-disciplinary aerospace workforce development.鈥 She is currently director of the Washington NASA Space Grant Consortium, co-director of the 91爆料 Space Policy and Research Center and chair of the AIAA Aerospace Department Chairs Association. She is also a member of the WSAS education committee.

鈥淚 am excited to serve on the WSAS board and work with WSAS members to leverage and grow WSAS鈥檚 impact by identifying new opportunities for WSAS to collaborate and partner with the state in addressing the state鈥檚 needs,鈥 said Morgansen.

The new members to the Washington State Academy of Sciences will be formally inducted in September.

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91爆料 immunologist, mathematician among newly elected National Academy of Sciences members /news/2023/05/05/nas-2023/ Fri, 05 May 2023 22:38:26 +0000 /news/?p=81481 Two 91爆料 faculty members have been elected to the National Academy of Sciences:

  • 顿谤.听, professor of medicine and of immunology at the 91爆料, as well as the Rona Jaffe Foundation Endowed Chair at the Fred Hutchinson Cancer Center and head of the Program in Immunology in its Clinical Research Division
  • , the Robert R. and Elaine F. Phelps Endowed Professor in Mathematics at the 91爆料

Greenberg and Uhlmann are among 120 new members and 23 international members elected 鈥渋n recognition of their distinguished and continuing achievements in original research,鈥 May 2 by the academy. Chartered in 1863, the National Academy of Sciences provides policy advice and input to governmental, nonprofit and private organizations.

Philip Greenberg

Greenberg鈥檚 laboratory is internationally respected for its work on T-cell therapies for cancer and chronic infections. A type of white blood cell, T cells are part of the body鈥檚 defenses. His team is identifying tumor antigens 鈥 or substances that provoke immune responses 鈥 that could be targets for T cells and the basis of anti-cancer therapies. Clinical trials of T-cell therapies are currently underway for patients with small cell lung cancer, malignant melanoma and acute leukemia 鈥 along with preclinical research for ovarian and pancreatic cancers. Greenberg鈥檚 research also focuses on developing techniques to monitor T-cell infusions for potential obstacles to immune therapy. Other work includes seeking ways to erase immune 鈥渕emory鈥 in T cells and reprogram them with another immune response. He is also testing strategies to activate natural killer cells 鈥 another immune system component 鈥 against cancer.

Greenberg earned a bachelor鈥檚 degree from Washington University in St. Louis and an M.D. from SUNY Downstate Health Sciences University. He was a medical resident, and later a postdoctoral researcher, at the University of California, San Diego, before joining Fred Hutch as a clinical and research fellow in oncology. Greenberg was recently named president of the American Association for Cancer Research.

Gunther Uhlmann

Uhlmann is a world-renowned expert in inverse problems, which involves calculating the causal factors behind a set of observations. Among other applications, Uhlmann has explored identifying an object by how it scatters light and other electromagnetic waves. As part of these efforts, he has formulated theories for certain types of cloaking technologies, some of which have been realized. He has also worked on partial differential equations, imaging and microlocal analysis.

Uhlmann earned a degree in mathematics from the University of Chile in 1973 and a doctoral degree in mathematics from the Massachusetts Institute of Technology in 1976. Beginning his academic career at MIT, he joined the 91爆料 faculty in 1984, and held the Walker Family Endowed Professorship in Mathematics from 2006 to 2022. Since 2014, Uhlmann has been the Si Yuan Professor at the Hong Kong University of Science and Technology. He has also held chairs and professorships at Cambridge University, the University of Helsinki, the Paris Mathematical Science Foundation and the University of California, Berkeley. Among other honors, elected fellow of the American Mathematical Society in 2012 and fellow of the Society for Industrial and Applied Mathematics in 2010.

With this year鈥檚 additions, the National Academy of Sciences now has 2,565 active members and 526 international members.

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Four 91爆料 researchers named AAAS Fellows in 2022 /news/2023/01/31/four-uw-researchers-named-aaas-fellows-in-2022/ Tue, 31 Jan 2023 15:00:39 +0000 /news/?p=80525 head shot montage
Four 91爆料 researchers were named AAAS Fellows in 2022: From left to right 鈥 Emily M. Bender; John Marzluff; Sean D. Sullivan; Deborah Illman. Photo: 91爆料

Four 91爆料 researchers have been named AAAS Fellows, according to a Jan. 31 by the American Association for the Advancement of Science. They are among 506 new fellows from around the world elected in 2022, who are recognized for their 鈥渟cientifically and socially distinguished achievements鈥 in science and engineering.

A tradition dating back to 1874, election as an AAAS Fellow is a lifetime honor, and all fellows are expected to meet the commonly held standards of professional ethics and scientific integrity. The new fellows will be celebrated in Washington, D.C., in summer 2023.

This year鈥檚 91爆料 AAAS fellows are:

 

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Emily M. Bender

, professor in the Department of Linguistics, is honored for demonstrating the role of grammar in natural language processing (NLP), extending computational modeling to less-studied languages, and raising ethical issues in NLP 鈥 an interdisciplinary field concerned with the interactions between computers and human language. Bender studies the societal impacts of language technology, what it means for research and design of such technology, and how to include it in the NLP curriculum. She鈥檚 taught seminars on the topic and in 2021聽聽for the North American Chapter of the Association for Computational Linguistics. Bender鈥檚 areas of focus include data documentation and the dangers of specific technology, such as large language models and chatbots used for search. She has worked to make linguistics accessible to computer scientists in NLP, giving tutorials at major conferences and writing two associated books. Bender also studies how computational methods can serve the purposes of linguistic analysis and how linguistic knowledge can be used to improve the performance of natural language processing systems. She has led the development of the , a framework supporting the creation of broad-coverage, precision, implemented grammars for diverse languages. Her other interests include sociolinguistic variation, or the ways speakers manipulate their languages to create style and register.

 

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John Marzluff

, a professor of wildlife science in the 91爆料 School of Environmental and Forest Sciences, is honored for advances in our understanding of how humans impact birds, and for communicating the importance of birds to the public. Marzluff鈥檚 lab studies the relationship between humans and birds to discover how to best conserve wildlife in our modern, human-dominated world. He focuses primarily on corvids 鈥 ravens, crows and jays 鈥 but he has also worked with falcons and hawks throughout North America and tundra-nesting birds in the Arctic. Marzluff also is interested in all the ways that birds affect people. He has written a number of books for researchers and lay audiences, including 鈥淲elcome to Subirdia鈥 and 鈥淚n Search of Meadowlarks.鈥 Marzluff is a member of the board of editors for Ecological Applications, member of the U.S. Fish and Wildlife Service鈥檚 recovery team for the critically endangered Mariana crow, a fellow of the American Ornithologists鈥 Union and a National Geographic Society Explorer.

 

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Sean D. Sullivan Photo: 91爆料

, professor of pharmacy and of health services, is honored for his work on medical and drug coverage and reimbursement policies, as well as for developing studies to address complex medical questions. Sullivan, who served as the dean of the 91爆料 School of Pharmacy from 2014 to 2022, was elected in 2020 to the National Academy of Medicine. He was one of the few people from the pharmacy field named to the academy, among the highest honors in health and medicine. Sullivan is widely recognized for pioneering U.S. guidelines for evidence-based preferred drug lists, also known as drug formularies. With insurers, he created the value-based formulary, which emphasizes a drug鈥檚 clinical effectiveness rather than its cost, and was the first health economist to serve on panels for global respiratory guidelines, incorporating economic considerations into recommendations. His research focuses on health technology assessment, medical decision-making, and the economic evaluation of medical technology, including pharmaceuticals. A member of the 91爆料 faculty since 1992, Sullivan holds adjunct appointments in the School of Medicine and in the Public Health Sciences Division at the Fred Hutch Cancer Center. Sullivan is currently on sabbatical at the London School of Economics and Political Science, and will return to 91爆料 this fall.

Deborah Illman

is being recognized for excellence in science and technical communication as a practitioner, instructor and mentor, particularly for her dedication to the communication of science to the public. Her research and teaching activities at the 91爆料 focused on science communication and media coverage of science and technology. She developed and taught courses for undergraduate and graduate students on writing about science for general audiences as well as on scientific and technical communication. Most recently, she received a Professional Development Fellowship from the National Science Foundation (NSF) to study mental models of audience and decision-making in science and technology communication. Previously, her research on accuracy in science news reporting received support from the NSF Ethics and Values Program in Science, Technology, and Society. Illman also directed the Chemistry Communication Leadership Institute, and in 2006, with funding from an , she focused on communicating about large and long-term multidisciplinary research efforts using the NSF Science and Technology Centers as a case study. Illman is a former Associate Editor of Chemical & Engineering News, the official news publication of the American Chemical Society, and she was founding editor of .

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91爆料鈥檚 Daniel Chen, 鈥22, named prestigious Marshall Scholar /news/2022/12/12/uws-daniel-chen-22-named-prestigious-marshall-scholar/ Mon, 12 Dec 2022 15:00:33 +0000 /news/?p=80232 profile image
Daniel Chen, class of 2022, was selected as a Marshall Scholar. Photo: 91爆料

91爆料 alumnus Daniel Guorui Chen, Class of 2022, has been named a, one of the highest honors available to college graduates in the U.S. Chen plans to attend the University of Cambridge.

鈥淚 was so surprised when I learned I was awarded. This is such an honor,鈥 Chen, 19, said. 鈥淭he Marshall Scholarship is a great example of taking U.S. and U.K. perspectives and putting them together to work and discover and push for better health, not just for these two countries, but for the world at large.鈥

Founded by an act of the British Parliament in 1953, the awards pay all expenses for up to three years of study at a British university of the student鈥檚 choice. Marshall scholarships finance young Americans of high ability to study for a degree in the United Kingdom. This year, 40 scholars were selected to pursue graduate study in any field at a UK institution.

Chen, a Sammamish, Wash., native, graduated with majors in informatics (data science) and microbiology. He plans to pursue a Master of Philosophy degree at Cambridge, delving deeper into biological sciences and genomic medicine. Eventually, Chen hopes to earn an M.D. and a Ph.D., to become a physician-scientist and professor conducting research while practicing in clinic.

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Daniel Chen Photo: 91爆料

Chen is the first 91爆料 student to achieve this honor since Havana McElvaine was selected in 2018. Prior to that, 91爆料鈥檚 Jeffrey Eaton was selected in 2008. This year, 951 students from across the United States applied for the scholarship. Only four candidates from the San Francisco region, which includes Washington, Alaska, Idaho, Montana, Northern California and most of Nevada, were selected.

鈥淒aniel鈥檚 rigorous undergraduate scholarship on topical and complex medical issues is exemplary,鈥 said Ed Taylor, vice provost and dean of Undergraduate Academic Affairs. 鈥淭his recognition will provide a wonderful opportunity for Daniel, who is already dedicated to the medical sciences, to deepen and extend his scholarship.鈥

 

Read more about Chen here.

 

Chen arrived at the 91爆料 when he was 14, through the Early Entrance Program. During his undergraduate career, he conducted research at 91爆料 and at some of the most prestigious research labs in the Puget Sound region, including聽 the, Institute for Systems Biology and the. Chen鈥檚 research examines how and why some people contract long COVID and what鈥檚 happening at the cellular level. He also conducted single-cell research on pancreatic cancer and COVID-19 patients, and gained experience in bacterial cloning and genetic engineering while working in a medical microbiology lab.

鈥淒aniel is an amazing young scientist,鈥 said James R. Heath, president of the ISB and one of Chen鈥檚 mentors. Chen was the second author out of more than 50 on a research paper, 鈥,鈥 published in 2020 in Cell.

 

For media: B-roll and soundbites of Chen available .

 

Greg Hay, an assistant teaching professor in the Information School, asked Chen to be a teaching assistant after he exceled during an introductory class. Later, Hay tapped Chen to lead a project supervising both undergraduate and graduate students.

鈥淒aniel has a superpower processor,鈥 Hay said. 鈥淗is mind is always active, engaged and blasting forward at double-speed. He is fearless, focused and curious.鈥

While in Britain, Chen plans to study with of the to acquire an understanding of the computational biology toolkit. He said he鈥檚 looking forward to immersing himself in British culture and learning from people who are different from him. He believes that a diversity of thought is what 鈥渄rives knowledge forward.鈥

鈥淲hen we come from different backgrounds and perspectives, we can work together to chip away at the truth,鈥 Chen said. 鈥淭ogether we can figure out rich solutions.鈥

Chen was the recipient of the Goldwater Scholarship, Mary Gates Research Scholarship, Microbiology Undergraduate Research Award and Levinson Emerging Scholar Award. He received the Microbiology Erling J. Ordal Award for best senior thesis, a Washington Research Foundation Fellowship and a Microbiology Summer Interdisciplinary Research Fellowship. In 2022, he was named to the Husky 100. Chen, who identifies as LGBTQIA+, also co-founded , a student group that promotes visibility and acceptance of neurodiversity at the 91爆料 and beyond.

For more information, contact Jackson Holtz at jjholtz@uw.edu.

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Clinical trials brought us COVID vaccines, but we鈥檙e in largescale population ‘trials’ now and will learn more /news/2021/05/07/clinical-trials-brought-us-covid-vaccines-but-were-in-largescale-population-trials-now-and-will-learn-more/ Fri, 07 May 2021 18:25:42 +0000 /news/?p=74253 Scientists can learn a lot in a controlled clinical trial involving tens of thousands of people, such as the COVID-19 vaccine trials that led to their approval, but we will all learn a lot more as hundreds of millions of people are vaccinated. And, some of what might turn up in this population-based data are adverse side effects, such as the blood clotting suffered by nearly 20 people out of roughly 8 million who received the Johnson & Johnson vaccine.

Larry Corey

鈥淲hen a mass vaccination campaign is rolled out, adverse events are observed more acutely and more accurately than during the slow trickle that goes with any other kind of vaccine or drug distribution. The infrequent becomes more frequent because the number of people vaccinated in a very short time is so large 鈥 a one-in-a-million problem becomes one per day rather than one every two to six months,鈥 writes the 91爆料鈥檚聽聽in a recent聽,聽jointly produced by Johns Hopkins University and the 91爆料.

The key to catching adverse effects is an effective surveillance system, which worked in the blood-clotting case and must continue to be supported with time, energy and resources.

鈥淭he advantage we have at this point is that we know how to diagnose and treat it, so there鈥檚 at least a potential to lessen the impact of the disease,鈥 Corey wrote in . 鈥淎 thorough review of the risk benefit of the vaccines was performed by both the CDC and the FDA and both of these organizations advised that people should be alerted about the possibility of (blood clotting) and to seek medical evaluation if they experience prolonged abdominal pain, worsening headache, or shortness of breath in the days following vaccination.鈥

This should improve public confidence that these vaccines, including the Johnson & Johnson vaccine which was put back into circulation, are still being monitored for effectiveness and safety. And, Corey points out, while adverse effects will be investigated and vaccines evaluated in light of them, the risk-to-benefit ratio of the vaccines needs to be kept in perspective. After all, the odds of being hit by a car are about one in 4,292 and dying as a result are about one in 47,273.

鈥淐linical trials have given us a wealth of information about the efficacy and safety profile of vaccines for COVID-19. But the work of gathering evidence and weighing results in the context of an ongoing pandemic isn鈥檛 done,鈥 said Corey.

To read this and other articles by Corey and other experts, visit the聽 blog series created by Johns Hopkins and the 91爆料 as an outcome of the joint symposium 鈥斅Preserving the Scientific Integrity of Getting to COVID-19 Vaccines: From Clinical Trials to Public Allocation聽鈥 the two universities hosted in October.

Dr. Larry Corey is the leader of the聽聽(CoVPN ) Operations Center, which was formed by the National Institute of Allergy and Infectious Diseases at the U.S. National Institutes of Health to respond to the global pandemic and the Chair of the ACTIV COVID 19 Vaccine Clinical Trials Working Group. He is a Professor of Medicine and Virology at 91爆料 and a Professor in the Vaccine and Infectious Disease Division and past President and Director of Fred Hutchinson Cancer Research Center.

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Vaccines debate: 鈥楨scape variants鈥 of the coronavirus are a serious future threat /news/2021/04/13/covid-19-vaccines-escape-variants-of-the-coronavirus-are-a-serious-future-threat/ Tue, 13 Apr 2021 17:15:48 +0000 /news/?p=73800
Should doses of the two-shot vaccines be spread out by months instead of weeks to get more first shots in shoulders?

With COVID-19 cases again in many parts of the country 鈥 including Washington state where were pushed back to Phase 2 effective Friday 鈥 there鈥檚 a growing between continuing to give both doses of Moderna or Pfizer-BioNTech vaccines close together, or giving them months apart in order to get first shots in more shoulders faster.

The argument for giving more people the first dose before circling back months later to give the second, which provides the strongest protection against COVID-19, centers on the numbers: It鈥檚 better, the argument goes, for more people to be partially protected in order to curb infections by the coronavirus than to have fewer people fully vaccinated. Advocates of this hope partial vaccinations would not only curb infections but also save lives, since a single dose significant protection against illness.

Under the current strategy, the second dose of either two-dose vaccines comes within a few weeks of the first shot. The dose-sparing strategy, considered either because a community has too few doses or climbing infections, schedules the second dose for months later.

Larry Corey

However, the dose-sparing strategy could create even greater trouble than we鈥檙e currently facing, argues the 91爆料鈥檚聽聽in a recent聽聽jointly produced by Johns Hopkins University and the 91爆料.

鈥淚 say that because the viruses we鈥檙e going to encounter today and what we will encounter in the next several months are not the same viruses that we tested the vaccines on and upon which the single-dose [strategy] data are based; they are going to be more formidable adversaries,鈥 writes Corey, a professor of medicine and virology at the 91爆料 School of Medicine.

These future versions of the viruses are 鈥渆scape variants鈥 that have evolved in the environment of weak immune responses 鈥 the body in this case has produced a strong enough immune response to tamp down the infection but not strong enough to keep mutated viruses from spreading.

鈥淗ow do we overcome escape variants? We do so by using the full strength of the tools we have available to us. We provide immunity that is capable of eliminating the virus quickly and we don鈥檛 expose the virus to lots of people with low levels of immunity,鈥 Corey writes.

Corey adds that the coronavirus variants currently spreading require a stronger immune response to beat, and current versions of the two-dose vaccines were designed to battle the original versions of the virus. So, using one dose to create partial immunity to a variant that requires a stronger immune response to beat could create an environment for new, tougher variants to evolve and spread. However, giving the second dose creates a much stronger immune response and can stop escape variants.

鈥淲hile my musings are inferential, I feel we will actually do more harm than good by markedly increasing the population of people with partial protective immunity,鈥 Corey writes.

To read this and other articles by Corey and other experts, visit the聽 blog series created by Johns Hopkins and the 91爆料 as an outcome of the joint symposium 鈥斅Preserving the Scientific Integrity of Getting to COVID-19 Vaccines: From Clinical Trials to Public Allocation聽鈥 the two universities hosted in October.

Dr. Larry Corey is the leader of the (CoVPN ) Operations Center, which was formed by the National Institute of Allergy and Infectious Diseases at the U.S. National Institutes of Health to respond to the global pandemic and the Chair of the ACTIV COVID 19 Vaccine Clinical Trials Working Group. He is a Professor of Medicine and Virology at 91爆料 and a Professor in the Vaccine and Infectious Disease Division and past President and Director of Fred Hutchinson Cancer Research Center.

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Dr. Anne McTiernan releases memoir, ‘Cured: A Doctor’s Journey from Panic to Peace’ /news/2021/03/09/dr-anne-mctiernan-releases-memoir-cured-a-doctors-journey-from-panic-to-peace/ Tue, 09 Mar 2021 17:38:10 +0000 /news/?p=73172
“Cured: A Doctor’s Journey from Panic to Peace” was published by Central Recovery Press.

Balancing motherhood and medical school is a challenge, but panic attacks and memories of childhood trauma make the path all the more difficult. With therapy, found her way through. Now she discusses her experiences in an intimate memoir, “.”

McTiernan is a research professor of epidemiology in the 91爆料 School of Public Health and professor at the Fred Hutchinson Cancer Research Center. She studies diet, obesity, exercise, and risk for cancer development and prognosis. “Cured” was published in February by Central Recovery Press.

Anxiety and stress were not her only challenges. The book, publisher’s notes say, also “calls out the 鈥 stigma surrounding the mental health of physicians, sexism in the medical field, and the imbalance of the health care system when it comes to race and class.”

91爆料 Notebook asked McTiernan about the book and her experience writing such a personal story.

This is a deeply personal memoir. Why did you decide to share your story, and was the writing process difficult emotionally?

The major themes in “Cured” 鈥 motherhood, sexism, mental health 鈥 are as relevant today as when the story takes place. Unfortunately, women still struggle to balance taking care of children and taking care of their careers, and have to handle work while dealing with the belittling effects of sexism.

And medical students, residents, fellows, and physicians still have to deal with their mental health with little help because the system requires them to keep their issues secret and encourages them not to seek professional treatment. I wanted to bring all this to light.

Some of the writing was emotionally difficult, especially when recounting the panic attacks, because in order to give the details I felt like I was reliving them. Other parts of the memoir writing were very enjoyable, such as recalling the joys of mothering such wonderful children.

Anne McTiernan's memoir, "Cured."
Dr. Anne McTiernan

What writing habits proved successful? And how did you know you were done?

As a researcher, I have learned to work very well with deadlines. Everything has a timeline 鈥 grants, conferences, journal papers. So, having a timeline from my publisher was very helpful. I was also lucky to work with a developmental editor (Jennifer Munro) who provided early feedback which helped me make early progress.

It’s always a challenge to know what to put into a memoir and what to leave out. I’ve taken several courses on memoir writing, including through , that taught me how to craft life story into an arc.

What do you hope readers will take away from your memoir?

I hope that readers will understand the importance of balancing various aspects of life, to realize that it鈥檚 not critical to be best in everything. This is especially important today with the challenges people have in trying to work, stay healthy and take care of loved ones. It鈥檚 important to give yourself slack.

During COVID, it’s a major accomplishment just to continue to put food on the table and follow public health guidelines to curtail the virus, and to keep yourself relatively sane.

I hope the medical community will realize the critical importance of supporting mental health for physicians, realizing that the expectations for trainees and physicians put people at high risk for stress-induced symptoms.

For more information, contact McTiernan at amctiern@fredhutch.org.

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COVID-19 vaccines are 鈥榬emarkable achievement,鈥 but soothing mistrust is necessary to end pandemic /news/2021/01/08/covid-19-vaccines-are-remarkable-achievement-but-soothing-mistrust-is-necessary-to-end-pandemic/ Fri, 08 Jan 2021 23:18:40 +0000 /news/?p=72214 鈥淥f course, we didn鈥檛 put Democrats in the vial; we didn鈥檛 put Republicans in the vial,鈥 91爆料鈥檚聽 writes in a recent聽聽jointly produced by Johns Hopkins University and the 91爆料.

While development of vaccines now being distributed to combat COVID-19, the deadly disease caused by the novel coronavirus, are a 鈥渞emarkable achievement鈥 that demonstrate the power of science to save lives, mistrust and fear continue to cause nearly to say they would be unlikely to get vaccinated.

Larry Corey

Some of that mistrust stems from before the pandemic, but unfortunate politicization of COVID-19 vaccine development is also to blame. When the current administration jumped in to claim credit for the rapid development of the vaccines, that act personalized the science behind its creation.

鈥淏y personalizing it, it became politicized. It created an odd discord, as if science 鈥 and what is in a vial 鈥 had something to do with whether you鈥檙e a Republican or Democrat,鈥 writes Corey.

Also, the administration put an enormous amount of funding into the rapid development of vaccines, but then named the effort Operation Warp Speed. And, says Corey, speed in medical scientific development 鈥渋s not something we associate with positive outcomes.鈥

So, given the historic mistrust of vaccinations, the politicization of COVID-19 vaccines and an unfortunate project name, vaccine hesitancy is understandable. And yet the pandemic rages on. How, then, to bridge the divide between jubilation at the production of incredibly successful vaccines and mistrust?

鈥淚t will take work by all of us 鈥 in the scientific community and in the broader public. It will take hard work to convey the importance of vaccination. It will take time to rebuild trust across the divide. And it will take a public open to healing discourse; a public who remains curious and eager to know more as we learn more. Because we will,鈥 Corey writes.

To read this and other articles by Corey and other experts, visit the聽 blog series created by Johns Hopkins and the 91爆料 as an outcome of the joint symposium 鈥斅犅犫 the two universities hosted in October.

Dr. Larry Corey is an internationally renowned expert in virology, immunology and vaccine development and a leader of the聽聽(CoVPN), which was formed by the National Institute of Allergy and Infectious Diseases at the U.S. National Institutes of Health to respond to the global pandemic. He is a professor of medicine and virology at 91爆料 School of Medicine and a professor in the Vaccine and Infectious Disease Division and past president and director of Fred Hutchinson Cancer Research Center.

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COVID-19 vaccines may not prevent spread of virus, so mask-wearing, other protections still critical /news/2020/12/02/covid-19-vaccines-may-not-prevent-spread-of-virus-so-mask-wearing-other-protections-still-critical/ Wed, 02 Dec 2020 23:22:28 +0000 /news/?p=71782 Excitement and relief over that help prevent people from getting sick, winding up in the hospital or dying from COVID-19, the disease caused by the coronavirus, are warranted, says 91爆料鈥檚 . But, these messenger RNA (mRNA) vaccines may not prevent people from getting infected or spreading the virus.

Larry Corey

Answering questions around how vaccines affect transmission of the virus is 鈥渙f obvious importance鈥 and research will be conducted once people begin getting vaccinated, Corey writes in a new jointly produced by Johns Hopkins University and the 91爆料. But we all must still聽wear masks, physically distance, wash our hands frequently, and avoid large gatherings 鈥 even when most people have been vaccinated.

鈥淚f vaccinated individuals are capable of transmitting infection,鈥 Corey writes, 鈥渢hen anybody who is not vaccinated fares no differently before than after the introduction of a COVID-19 vaccine. With vaccine hesitancy resulting in fewer people agreeing to be vaccinated, we do not yet know whether and when we will be able to markedly reduce the public health implications of COVID-19 and reduce its circulation in the workplace, in close communities and stop super-spreading events.鈥

In addition, Corey notes that mathematical models suggest that vaccines could create a situation in which many more people carry the virus without showing symptoms, become more cavalier about whether they can spread the virus and therefore unknowingly infect even more people.

鈥淭his realization helps explain why we must optimize coverage and overcome vaccine hesitancy, especially in persons who are at high risk,鈥 Corey writes.

To read this and other articles by Corey and other experts, visit the blog series created by Johns Hopkins and the 91爆料 as an outcome of the joint symposium 鈥 鈥 the two universities hosted in October.

Dr. Larry Corey is an internationally renowned expert in virology, immunology and vaccine development and a leader of the (CoVPN), which was formed by the National Institute of Allergy and Infectious Diseases at the U.S. National Institutes of Health to respond to the global pandemic. He is a professor of medicine and virology at 91爆料 School of Medicine and a professor in the Vaccine and Infectious Disease Division and past president and director of Fred Hutchinson Cancer Research Center.

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